A study into the safety, efficacy and tolerability of scalp cooling in patients receiving chemotherapy, through the reduction of chemotherapy induced alopecia. (#353)
Vicki Durston
1
,
Michelle White
,
Jane Fletcher
- Cabrini, Brighton, Vic, Australia
Background:
Chemotherapy-induced alopecia is one of the most distressing side effect for patients. Scalp cooling is an effective method for preventing chemotherapy-induced alopecia, and is widely used in the UK and Europe.
Aim:
To determine the efficacy and tolerability of scalp cooling in patients with early breast cancer receiving chemotherapy at the Cabrini Brighton Day Oncology Service. A secondary aim was evaluate patient wellbeing and quality of life.
Method:
This was an open label non-randomised cohort study. A series of self-report questionnaires including, hair loss, quality of life measures, a demographic and registration questionnaire, and a range of questions about expectation, satisfaction and aspects of most benefit (post study questionnaire) of the scalp cooling procedure were administered at multiple time points.
Results:
A total of 34 patients completed the pre-trial evaluation
- 24 patients went on to complete the scalp cooling trial
- 5 patients discontinued due to intolerability
- 5 patients decided not to commence the trial
Self Reported Hair Loss Results:
-12% had no hair loss
- 23% had minimal hair loss
- 65% had moderate hair loss
There were no patients whom experienced total hair loss
100% patients that completed the trial were happy with the end result, describing being able to keep their hair, (even if only partially) as a great result.
Side effects were minimal and all patients would recommend the trial to other patients.
Conclusion: Results from the evaluation of the trial indicated a positive response, with excellent feedback from patients. As a result, scalp cooling has now become standard practice at both Cabrini Day Oncology units for all patients eligible to utilise this technology.
- 1. Trueb, RM, 2010: Chemotherapy-induced hair loss. Skin Therapy Lett 2010;15:5-7.
2. Pickard-Holley,S (1995) The symptom experience of alopecia, Seminar Oncology Nurse (11)(4), 235 -8
3. Cello, D ,1993: The Functional Assessment of Cancer Therapy scale: development and validationof the general measure. Journal of Clinical Oncology