A study into the safety, efficacy and tolerability of scalp cooling in patients receiving chemotherapy, through the reduction of chemotherapy induced alopecia. (#353)
Chemotherapy-induced alopecia is one of the most distressing side effect for patients. Scalp cooling is an effective method for preventing chemotherapy-induced alopecia, and is widely used in the UK and Europe.
To determine the efficacy and tolerability of scalp cooling in patients with early breast cancer receiving chemotherapy at the Cabrini Brighton Day Oncology Service. A secondary aim was evaluate patient wellbeing and quality of life.
This was an open label non-randomised cohort study. A series of self-report questionnaires including, hair loss, quality of life measures, a demographic and registration questionnaire, and a range of questions about expectation, satisfaction and aspects of most benefit (post study questionnaire) of the scalp cooling procedure were administered at multiple time points.
A total of 34 patients completed the pre-trial evaluation
- 24 patients went on to complete the scalp cooling trial
- 5 patients discontinued due to intolerability
- 5 patients decided not to commence the trial
Self Reported Hair Loss Results:
-12% had no hair loss
- 23% had minimal hair loss
- 65% had moderate hair loss
There were no patients whom experienced total hair loss
100% patients that completed the trial were happy with the end result, describing being able to keep their hair, (even if only partially) as a great result.
Side effects were minimal and all patients would recommend the trial to other patients.
Conclusion: Results from the evaluation of the trial indicated a positive response, with excellent feedback from patients. As a result, scalp cooling has now become standard practice at both Cabrini Day Oncology units for all patients eligible to utilise this technology.
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